Friday, September 27, 2019

Micro economics price in a competitive market Essay

Micro economics price in a competitive market - Essay Example A sales subsidy, paid on a per unit basis to sellers, creates a subsidy wedge between the price that the market will pay (P1), and the price that the suppliers will receive (P2). The per-unit subsidy will also shift the supply curve to the right, from S1 to S2, depending on the magnitude of the subsidy. The benefit of the price subsidy is usually shared by the market buyers and the suppliers, with the allocation of the benefits depending on the balance of the elasticities of the demand and supply for the product. B. From society's point of view, the per-unit subsidy paid to the sellers will prove to be more beneficial than the statutory minimum price that is set above the market-clearing price. The subsidy shifts the supply curve to the right, and provides either (or both) the buyers (market) and the sellers (suppliers) benefits from the subsidy. On the other hand, the price floor set above the market-clearing price creates surpluses, leading to an inefficient allocation of resources and to the unfortunate scenario where the government will be forced to purchase the surplus goods.

Thursday, September 26, 2019

Fashion Marketing Essay Example | Topics and Well Written Essays - 1000 words

Fashion Marketing - Essay Example The essay "Fashion Marketing" concerns the marketing in fashion. With a success story that continues even today, Hanes has defined the clothing industry like no other company ever has. Hanes, in 2012 used the social medium Facebook to help grow their relationship with their consumers. Underwear isn’t the first thing you would think of when listing your passions, but Hanes thought it can build an â€Å"emotional connection† with underwear shoppers and get them talking. This type of marketing succeeded. Social media, like Facebook, is at the center of this strategy. On Facebook, where it has 2.5 million likes asked open-ended questions on what your favorite underwear type is or posts that ask you to share your first experience wearing a bra. The brand is trying to get consumers talking. â€Å"Hanes wants to be able to connect with consumers beyond just the transaction,† said David Robertson, director of marketing at Hanes. â€Å"We want to communicate what the bra nd stands for. We want to hear from them and we want to establish more of an emotional connection. That ongoing relationship will lead to increased loyalty and advocacy.† H&M opened its first store in Sweden. Hennes, the name at the time specialized in women’s fashion. The franchise slowly grew opening its first store outside of Sweden in 1963. Today the company has over 2,800 locations worldwide and they specialize in clothing for women, men, and kids, and now underwear. In 2013, H&M incorporated location-based campaigns into their marketing mix.

ECONOMICS Essay Example | Topics and Well Written Essays - 2000 words

ECONOMICS - Essay Example It will be indeed an insightful experience to delve on the ideologies and factors that made the Western Europe the crucible of economic development, social welfare and political liberalism, while pushing the Eastern Europe in the background, marred by economic underdevelopment, large scale dearth and poverty and pervasive autocratic regimes. The good thing is that one could readily identify a series of salient influences responsible for such massive differences in these two land masses. However, it is not strictly possible to arrange these events and influences in a sharp and certain chronological arrangement because many of them tend to overlap each other. Hence, in an academic scenario, the disparities between what is known as the Western Civilization and its twin brother, the Eastern Europe are to a large extent the progeny of a range of influences and events like the Industrial Revolution, the interplay of capitalism and communism, the Soviet Revolution, the Great Depression, Wor ld War II, Cold War, Globalization, to name just a few. Industrial Revolution indeed happened to be a turning point in the history of 19th century Europe. However, the historical literature is replete with conjectures as to what made the Industrial Revolution have such a widespread sway in the Western Europe and North America, while it left the Eastern Europe largely untouched. Industrial Revolution that began in Britain soon spread across Western Europe and North America. One plausible reason why the Industrial Revolution had its genesis in the Western Europe is the cultural and economic influences of Renaissance that left the Western Europe in possession of the requisite capital and the popular mindset required to fuel it (Stearns 5). In contrast the Eastern Europe largely remained bereft of such influences. Besides, the Western Europe was less stymied by autocratic regimes, absolute monarchies and political instability, unlike the Eastern Europe, which allowed the Western nations to dedicate their efforts and resources to the task of fomenting economic growth and development (Stearns 54). Contrary to this the Eastern Europe evinced much political instability in the times which if given a change could have drastically altered its economy and culture. The socio-political environment of the 19th century Western Europe was amply conducive for the technological breakthroughs that fueled the Industrial Revolution (Stearns 44). Besides, the influx of the Industrial Revolution in the Western Europe gave way to a propitious cycle that led to widespread alterations in the cultural norms and values, making the West European nations more egalitarian, progressive and forward looking. Yet, this was not the case with Eastern Europe that largely remained parochial, insulated and agricultural, failing to open up its gates to the influences that were altering its Western sibling. The other big factor that stimulated the Industrial Revolution in the Western Europe was the fac t that the nations in this region happened to be dominant colonizing powers that had under their sway many colonies that furnished the much needed resources and raw materials required to support the ongoing Industrial Revolution (Stearns 36). In contrast the East European nations had no record of being colonizing powers, a factor that could have made them look for inspiration beyond their borders. The other big fa

Wednesday, September 25, 2019

Starbucks corporation Essay Example | Topics and Well Written Essays - 1500 words

Starbucks corporation - Essay Example In relation to the study the company which has been selected is Starbucks. Founded in 1971 and operating in more than 50 countries worldwide, Washington based Starbucks is the largest coffee retailer in the world at present. Starbucks has more than 16000 outlets all over the world. Out of these 16000 stores, nearly 12,000 stores are located across North America, South America, Europe, Middle East and the Pacific. In America, they have coffee outlets virtually in every corner. In other words, America is a saturated market for Starbucks now and they are looking for overseas markets as part of their expansion. In addition to coffee, Starbucks has other products such as tea, cake, cake filling leather goods, beverages, food, confections, coffee related machineries such as expresso machine, stainless steel coffee filters etc. Starbucks Corporation is a profitable organization, earning more than $600 million in 2004. The company generated revenue of more than $5000 million in the same year . Starbucks was one of the Fortune Top 100 Companies to Work For in 2005. In 1992, Starbucks listed on the stock exchange. Since then, its growth was phenomenal. Its annual average growth rate is 20% and profit growth is around 30%. Its share price marked a record 3500% increase, since its listing on the stock exchange. In other words, the market value of Starbucks shares from increased from $400 million to $15 billion recently. Starbucks is a reputed company with huge brand value and enormous resources. Its major strength is the ability to forecast market trends correctly and to make changes in business strategies. It should be noted that Starbucks was one among the few American companies which was unaffected by the recent recession. Starbucks top management team is extremely smarter in guiding the company even in unfavorable market conditions. Not even a single management decision went wrong for Starbucks in the last decade. Satisfied employees are another strength of Starbucks. à ¢â‚¬Å"They always treat the employees as their partners as mentioned earlier. Firm strategy, executive compensation and the performance of the firm can be divided into different streams and fit between firm strategy and compensation system is one among them† (Rajagopalan, n.d., p.4). Moreover, Starbucks is a socially committed company which gives something in return to the communities in which it operates. They are eager to recycle all industrial wastes produced by their activities. Smart business strategies, good suppliers, efficient leadership, talented employees are some other major strengths of Starbucks. Through the selling of coffee-related products such as brewing equipment and accessories, many consumers can enjoy high quality coffee at home rather than traveling out of their way. The equipment available includes Expresso machines, stainless steel coffee filters, and Starbucks cleaner and canisters. This is another example of how Starbucks is meeting the needs of curre nt customers as well as increasing its attractiveness to potential customers (Kembell, 2002). Weakness â€Å"Starbucks products are expensive compared to their competitor’s products (Starbucks Swot Analysis, n. d)†. One of the major weaknesses of Starbucks is the heavy pricing of their products. Starbucks never bothered to reduce the prices of their products irrespective of the market conditions. They do believe that for quality products, heavy pricing may not affect the customers very much. Starbucks is trying to implement the same price which they charge in America for coffee products, in international markets also. They are forgetting the fact that America is a wealthy country and the per capita income of Americans is more than that of the people in other countries. In other words, they are thinking that same product needs same pricing everywhere in the

Tuesday, September 24, 2019

Market Model Patterns of Change Essay Example | Topics and Well Written Essays - 750 words

Market Model Patterns of Change - Essay Example This paper aptly examines the patterns of change in the Wal-Mart market model. Wal-Mart is a perfect example of a business operating in an oligopolistic market structure. This is because they have low prices in the market enabling them compete healthily with other businesses dealing in similar products/services. Secondly, Wal-Mart operates with fewer sellers in the market giving them mutual interdependence over the other firms in the business. The long term effect of Wal-Mart operating an oligopoly will result to rise of economies of scale.This is because they will take advantage of having been in the markets to put barriers to other business wishing to join the business. Secondly, Operating under oligopoly market structure, Wal-Mart may collude to form a monopoly form of market structure, therefore, dictating their terms in the market. As a short term effect, Wal-Mart will be forced to renew their strategies of working because they will be facing different competitors in the market (Roberts & Berg, 2012). Secondly, Wal-Mart will enjoy controlling its market share for short period of time, but because the market is free for other to join, they will soon lose their popularity in the market as new firm producing same products will be cropping up to share the market it enjoyed. An example is that today, Wal-Mart may holds a substantial share in the market by its products but the case will be different in a year or two because there will be other new companies providing same products and at even better quality. There are various factors affecting the degree of competiveness of Wal-Mart. They involve both internal, external and delegations and functions of the management. The productive measures affecting Wal-Mart competitiveness is their capability in retailing. The business has various stores situated in various strategic places. These stores seek their profits by retailing their products through high volumes and using low mark-ups to give them a competitive advan tage over other business dealing in the same line of products. Secondly, Wal-Mart achieves their competitiveness owing to their standardized pallets, tight delivery schedules and computerized tracking. This has given them an edge over many businesses dealing in the same line since they are not in a position to raise enough capital to ensure efficiency in the systems. They are also able to use their technology as a source of marketing, therefore, minimize on their revenue spending. Thirdly, Wal-Mart prices play a significant role in influencing their activities and encouraging their competitiveness to other businesses. This is because it is an economy of scale, therefore, they purchase raw materials at a much cheaper price compared to other businesses that are not yet economies of scale. They also distribute their stock to a large numbers of stalls located strategically hence minimizing cost related to transport and other related activities. Being an economy of scale, Wal-Mart is off ering prices for its products that cannot rejected by the customers and in the process enjoys a large customer base for their products/services (Dunne, 2011). An accurate price determination of Wal-Mart’s competitors will significantly influence pricing decisions in Wal-Mart. The two chief competitors of Wal-Mart include

Sunday, September 22, 2019

Theory of Knowledge- To what extent does the vocabulary we have shape Essay

Theory of Knowledge- To what extent does the vocabulary we have shape what we know - Essay Example g with the first years of our lives we use words to express needs, dangers, feelings, to discover the use and practicality of the things surrounding us as well as to dive into the study of intellectual and scientific thought that has been developed and passed on to us for generations. Our vocabulary is not a simple collection of words and their meanings; it is also a complex tool that can shape what we can know through different areas of knowledge. Some may say though that words are unnecessary and of little importance in subjects such as mathematics, which expresses its reasoning through symbols, or the arts, which captures and conveys human feelings beyond verbal expression. However, I strongly believe that our vocabulary is an instrumental tool that shapes what we know and what we can know about the world we live in because it facilitates communication and it incorporates more meaning into our lives. I will discuss this statement in relation to three areas of knowledge: mathematic s, history and the arts. Mathematics is probably a subject that is least associated with the use of vocabulary. This is primarily because its core consists of developing certain ideas and principles through the use of numbers that connect though formulas, and which, at their turn, relate to one another in order to portray a logical picture of a certain phenomenon. Advanced mathematics can rarely find a direct application into the real world and it is mostly used for scientific development, because without the use of formulas and numbers we wouldn’t be at the technological level we are now. Some say that mathematics is a language by itself that claims universality. Therefore, one might state that our vocabulary has no power to shape what we know in this area of knowledge, that mathematics has made words obsolete and has raised above them. However, I believe that words are of outmost importance for children that learn basic mathematics. They learn how to add, subtract, multiply and

Saturday, September 21, 2019

Hypochlorite in Endodontics Essay Example for Free

Hypochlorite in Endodontics Essay Abstract Sodium hypochlorite (NaOCl) in various concentrations is the most widely used endodontic irrigant, but it can be an irritant to vital tissues. There are several reports about the complications of irrigation with NaOCl during root canal therapy. Most of the complications are the result of accidental extrusion of the solution from the apical foramen or accessory canals or perforations into the periapical area. This article is a review and comparison of all reported NaOCl accidents in the literature. The impetus behind root canal cleaning and shaping is the elimination of tissue remnants, bacteria, and toxins from the root canal system. This is generally accepted to be a major factor in the success of root canal treatment. Mechanical procedures alone are insufficient for total canal cleaning. Residual pulpal tissue, bacteria, and dentin debris may persist in the irregularities of canal systems. Therefore, irrigating solutions should support and complement endodontic preparation. These irrigants should flush out dentin debris, dissolve organic tissue, disinfect the canal system, and provide lubrication during instrumentation, without irritating the surrounding tissues. Some of the irrigants currently used include hydrogen peroxide, physiologic saline, water, sodium hypochlorite (NaOCl), chlorhexidine, and electrochemically activated water. Because of its physicochemical and antibacterial properties, NaOCl is one of the most popular irrigants. A 0.5% solution of NaOCl was used effectively during World War I to clean contaminated wounds.1 In 1920, Crane described the use of Dakins solution (NaOCl buffered with sodium bicarbonate) for root canal debridement and sterilization. Since then NaOCl has become a popular and effective intracanal irrigant.2 It is an inexpensive, readily available, and easily used chemical that usually rates well in research.3,4 A variety of NaOCl concentrations ranging from 0.5% to 5.25% have been advocated, as well as a variety of temperatures. The longer the solution can remain in contact with tissue, the higher the temperature of the solution, and the higher the concentration, the greater the ability of NaOCl to dissolve the tissue.5-7 The optimum concentration for use clinically is still a matter of controversy. Consequently, the clinician must decide on the concentration and temperature of the NaOCl and the potential consequences of this choice.5,8,9 Advantages of NaOCl The ability of NaOCl to dissolve organic soft tissue of the pulp and predentin is a result of oxidation. The powerful oxidative activity of hypochlorite not only dissolves the pulpal and dentinal tissue but also acts as a potent antimicrobial agent.3 It is well recognized to be effective against a broad range of pathogens: gram-positive and gramnegative bacteria, fungi, spores, and viruses including the human immunodeficiency virus.10 NaOCl, especially when used in high concentrations, is known to be effective in dissolving organic tissue remnants and disinfecting the canal system.4 Effective concentrations of NaOCl range from 2.6% o 5.25%. The dilution of NaOCl was suggested because it has been proved that concentrations over 0.5% are cytotoxic.11 Compared with a chlorhexidine gel, NaOCl not only has a higher capacity to kill microorganisms but is also more able to remove cells from the root canal.12 Water is not effective in removing dentine debris from grooves in the apical portio n of root canals.13 Disadvantages of NaOCl Acute inflammation followed by necrosis results when NaOCl comes into contact with vital tissue. It causes severe inflammation and cellular destruction in all tissues except heavily keratinized epithelium.5 The cytotoxic effect of 5.25% NaOCl on vital tissues, resulting in hemolysis, is well documented, and its use warrants proper care. The clinical efficacy of NaOCl relates to its nonspecific ability to oxidize, hydrolyze, and osmotically draw fluids out of tissues.5 The severity of the reaction depends on the concentration of the solution, its pH, and the duration of exposure. NaOCl has a pH of 11 to 12.5, which causes injury primarily by oxidation of proteins. In high concentrations, severe necrotic changes could be observed.14 The higher concentrations also have some irritating effects on the periodontal ligament.15 One report cites periodontal side effects of NaOCl with lower concentrations.16 However, when confined to the canal space as an intracanal endodontic irrigant, clinic al toxicity of NaOCl is no greater than the clinical toxicity of normal saline solution.6 NaOCl causes vascular permeability in blood vessels, probably as a result of damage to the vessels as well as the release of chemical mediators, such as histamine, from involved tissue. This characteristic causes immediate swelling and often profuse bleeding through the root canal when NaOCl is not used properly as an endodontic irrigant.17 There is only 1 report of hypersensitivity to NaOCl, which can easily be detected by skin patch testing.18 There are reports about the effects of improper use of NaOCl, including inadvertent injection into the maxillary sinus19 or splashing solution into the eyes.20 The extrusion of NaOCl can cause facial nerve weakness in addition to other soft-tissue damage.21 In addition to its toxicity to vital tissues, NaOCl has an unpleasant odor and causes damage if it comes into contact with clothing. 22 There are 2 reports of inadvertently injecting NaOCl instead of anesthetic solution. One resulted in severe palatal tissue necrosis,23 and the second involved edema in the pterygomandibular space and peritonsillar and pharyngeal areas because of mandibular block injection with NaOCl instead of anesthetic solution. In the second case, the patient was admitted to an intensive care unit for probable airway obstruction and given opioid analgesic intravenously for pain reduction.24 Damage to permanent tooth follicles, peripheral tissue, and oral mucosa have been reported during careless NaOCl use in pediatric endodontics. 25 There are only a small number of cases in the literature that have reported postoperative skin complications, long-term paresthesia, and altered nerve sensations arising from the use of NaOCl as an endodontic irrigant.26 There are 23 reported cases of NaOCl accidents in the literature.14,19,21,26-41 Almost all of the cases have similar sequelae including severe pain, edema, and profuse hemorrhage both interstitially and through the tooth. The reports mentioned several days of increasing edema and ecchymosis accompanied by tissue necrosis and paresthesia; in some cases, secondary infections have been observed. Most of the cases had complete resolution within a few weeks but a few were marked by long-term paresthesia or scarring. Remaining residual paresthesia indicates some permanent damage to the nerve endings in the affected area.36 NaOCl Accident Management Proper management of a NaOCl accident is important for achieving the best outcomes. The following lists some important factors for managing a NaOCl accident: †¢ †¢ †¢ †¢ †¢ †¢ Early recognition of the problem; the patient should be informed of the cause and nature of the accident (Table 2, see end of the article) Immediate irrigation of the canal with normal saline to dilute the NaOCl Allow bleeding response to flush the irritant out of the tissues Reassure patient Provide patient with both verbal and written home care instructions Monitor the patient After the NaOCl accident has been recognized and the patient has been informed, the authors recommend a treatment that focuses on palliative care, including cold and warm compresses, saline rinses, pain control, prophylactic antibiotics, steroid therapy, and monitoring (Table 3). It is important to reassure the patient throughout treatment because of the amount of time it will take for the inflammation to resolve. Avoiding NaOCl Accidents The following steps can help clinicians avoid NaOCl accidents: †¢ †¢ †¢ †¢ †¢ †¢ †¢ †¢ Adequate access preparation Good working length control Irrigation needle placed 1 mm to 3 mm short of working length Needle placed passively and not locked in the canal Irrigant expressed into the root canal slowly Constant in and out movements of the irrigating needle into the canal space Flowback of solution as it is expressed into the canal should be observed Use side delivery needles that are specifically designed for endodontic purposes Discussion NaOCl is tissue cytotoxic. When it comes into contact with tissue, it causes hemolysis and ulceration, inhibits neutrophil migration, and damages endothelial and fibroblast cells.14,42 Incorrect determination of working length, lateral perforation, and wedging of the irrigating needle are the most common procedural accidents associated with adverse NaOCl reactions.29 The optimal clinical concentration of NaOCl is still controversial. A 1% concentration of NaOCl provides tissue dissolution and an antimicrobial effect, but the concentration reported in the literature has been as high as 5.25%.43,44 Evidence demonstrates that high concentrations of NaOCl have enhanced antimicrobial activity.45 Irrigation time may increase the antimicrobial effect of endodontic irrigants without affecting the surrounding tissues. It has been found that 0.5% NaOCl had nearly the same bactericidal effect as 5.25% NaOCl when used for 30 minutes.46 After a NaOCl accident, early and aggressive treatment is advocated to reduce potentially serious complications. The use of antibiotics is recommended because there is a possibility of tissue necrosis and infection.47 Steroids also may be useful. Depending on the degree of injury, some cases might require surgical intervention. The aim of any surgical procedure should be to provide decompression and facilitate drainage, and to create an environment conducive to healing. The other advantage of surgery is meticulous debridement of grossly necrotic tissue and direct irrigation of affected sites.25 Conclusion NaOCl is an effective antibacterial agent but can be highly irritating when it comes in contact with vital tissue. Most of the reported complications occurred because of incorrect determination of endodontic working length, iatrogenic widening of the apical foramen, lateral perforation, or wedging of the irrigating needle. If a perforation or open apex exists, then great care should be exercised to prevent a NaOCl accident or an alternative irrigation solution should be considered. Table 2—How to recognize a NaOCl accident †¢ Immediate severe pain (for 2-6 minutes) †¢ Ballooning or immediate edema in adjacent soft tissue because of perfusion to the loose connective tissue †¢ Extension of edema to a large site of the face such as cheeks, peri- orbital region, or lips †¢ Ecchymosis on skin or mucosa as a result of profuse interstitial bleeding †¢ Profuse intraoral bleeding directly from root canal †¢ Chlorine taste or smell because of injected NaOCl to maxillary sinus †¢ Severe initial pain replaced with a constant discomfort or numbness, related to tissue destruction and distension †¢ Reversible or persistent anesthesia †¢ Possibility of secondary infection or spreading of former infection Table 3—How to treat a NaOCl accident †¢ Remain calm and inform the patient about the cause and nature of the complication. †¢ Immediately irrigate with normal saline to decrease the soft-tissue irritation by diluting the NaOCl. †¢ Let the bleeding response continue as it helps to flush the irritant out of the tissues. †¢ Recommend ice bag compresses for 24 hours (15-minute intervals)to minimize swelling. †¢ Recommend warm, moist compresses after 24 hours (15-minute intervals). †¢ Recommend rinsing with normal saline for 1 week to improve circulation to the affected area. †¢ For pain control †¢ Initial control of acute pain could be achieved with anesthetic nerve block. †¢ Acetaminophen-based narcotic analgesics for 3 to 7 days (NSAID analgesic should be avoided to decrease the amount of bleeding into the soft tissues). †¢ Prophylactic antibiotic coverage for 7 to 10 days to prevent secondary infection or spreading of the present infection. †¢ Steroid therapy with methylprednisolone for 2 to 3 days to control inflammatory reaction. †¢ Daily contact to monitor recovery. †¢ In severe cases such as respiratory distress, accessing the local emergency service via 911 is appropriate. †¢ Reassure the patient about the lengthy resolution of the inflammatory reaction. †¢ Provide the patient with both verbal and written home care instructions. †¢ Monitor the patient for pain control, secondary infection, and rea ssurance. References 1. Dakin HD. The use of certain antiseptic substances in treatment of infected wounds. Br Med J. 1915;2:318-320. 2. Crane AB. A Practicable Root Canal Technique. 1st ed. Philadelphia, Pa: Lea Febiger; 1920:69. 3. Mentz TC. The use of sodium hypochlorite as a general endodontic medicament. Int Endod J. 1982;15:132-136. 4. Ayhan H, Sultan N, Cirak M, et al. Antimicrobial effects of various endodontic irrigants on selected microorganisms. Int Endod J. 1999;32:99-102. 5. Thà © SD, Maltha JC, Plasschaert JM. Reactions of guinea pig subcutaneous connective tissue following exposure to sodium hypochlorite. Oral Surg Oral Med Oral Pathol. 1980;49: 460-466. 6. Nakamura H, Asai K, Fujita H, et al. The solvent action of sodium hypochlorite bovine tendon collagen, bovine pulp, and bovine gingiva. Oral Surg Oral Med Oral Pathol. 1985;60:322-326. 7. Pashley EL, Bridson NL, Bowman K, et al. Cytotoxic effects of NaOCl on vital tissue. J Endod. 1985;11:525-528. 8. Harrison JW, Svec TA, Baumgartner JC. Analysis of clinical toxicity of endodontic irrigants. J Endod. 1978;4:6-11. 9. Lamers AC, van Mullem PJ, Simon M. Tissue reactions to sodium hypochlorite and iodine potassium iodide under clinical conditions in monkey teeth. J Endod. 1980;6:788-792. 10. Resnik L, Veren K, Salahuddin SZ, et al. Stability and inactivation of HTLVIII/LAV under clinical and laboratory environments. JAMA. 1986;255:1887-1891. 11. Spangberg L, Engstrà ¶m B, Langeland K. Biologic effect of dental materials. 3. Toxicity and antimicrobial effect of endodontic antiseptics in vitro. Oral Surg Oral Med Oral Pathol. 1973;36:856-871. 12. Vianna ME, Horz HP, Gomes BP, et al. In vivo evaluation of microbial reduction after chemo-mechanical preparation of human root canals containing necrotic pulp tissue. Int Endod J. 2006;39:484-492. 13. van der Sluis LW, Gambarini G, Wu MK, et al. The influence of volume, type of irrigant and flushing method on removing artificially placed dentine debris from the apical root canal during passive ultrasonic irrigation. Int Endod J. 2006;39:472-476. 14. Gatot A, Arbelle J, Leiberman A, et al. Effects of sodium hypochlorite on soft tissues after its inadvertent injection beyond the root apex. J Endod. 1991;17:573574. 15. Tanomaru Filho M, Leonardo MR, Silva LA, et al. Inflammatory response to different endodontic irrigating solutions. Int Endod J. 2002;35:735-739. 16. Watts A, Paterson RC. Atypical lesions detected during a study of short-term tissue responses to three different endodontic instrumentation techniques. Endod Dent Traumatol. 1993;9:200-210. 17. Rutberg M, Spangberg E, Spangberg L. Evaluation of enhanced vascular permeability of endodontic medicaments in vivo. J Endod. 1977;3:347-351. 18. Kaufman AY, Keila S. Hypersensitivity to sodium hypochlorite. J Endod. 1989;15:224-226. 19. Ehrich DG, Brian JD Jr, Walker WA. Sodium hypochlorite accident: inadvertent injection into maxillary sinus. J Endod. 1993;19:180-182. 20. Ingram TA 3rd. Response of the human eye to accidental exposure to sodium hypochlorite. J Endod. 1990;16:235-238. 21. Witton R, Henthorn K, Ethunandan M, et al. Neurological complications following extrusion of sodium hypochlorite solution during root canal treatment. Int Endod J. 2005;38:843-848. 22. Serper A, Ozbek M, Calt S. Accidental sodium hypochlorite-induced skin injury during endodontic treatment. J Endod. 2004;30:180-181. 23. Gursoy UK, Bostanci V, Kosger HH. Palatal mucosa necrosis because of accidental sodium hypochlorite injection instead of anesthetic solution. Int Endod J. 2006;39:157-161. 24. Herrmann JW, Heicht RC. Complications in therapeutic use of sodium hypochlorite. J Endod. 1979;5:160-163. 25. Onà §aâ‚ ¬ O, Ho?gà ¶r M, Hilmioâ‚ ¬lu S, et al. Comparison of antibacteri al and toxic effects of various root canal irrigants. Int Endod J. 2003;36:423-432. 26. Reeh ES, Messer HH. Long-term paresthesia following inadvertent forcing of sodium hypochlorite through perforation in maxillary incisor. Endod Dent Traumatol. 1989;5:200-203. 27. Gernhardt CR, Eppendorf K, Kozlowski A, et al. Toxicity of concentrated sodium hypochlorite used as an endodontic irrigant. Int Endod J. 2004;37:272-280. 28. Hales JJ, Jackson CR, Everett AP, et al. Treatment protocol for the management of a sodium hypochlorite accident during endodontic therapy. Gen Dent. 2001;49:278-281. 29. Hà ¼lsmann M, Hahn W. Complications during root canal irrigation—literature review and case reports. Int Endod J. 2000; 33:186-193. 30. Mehra P, Clancy C, Wu J. Formation of facial hematoma during endodontic therapy. J Am Dent Assoc. 2000;131:67-71. 31. Kavanagh CP, Taylor J. Inadvertent injection of sodium hypochlorite to the maxillary sinus. Br Dent J. 1998;185:336-337. 32. Tosti A, Piraccini BM, Pazagglia M, et al. Severe facial edema following root canal therapy. Arch Dermatol. 1996;132:231-233. 33. Cymbler DM, Ardakani P. Sodium hypochlorite injection into periapical tissues. Dent Update. 1994;21:345-346. 34. Cali?kan MK, Tà ¼rkà ¼n M, Alper S. Allergy to sodium hypochlorite during root canal therapy: a case report. Int Endod J. 1994;27:163-167. 35. Linn JL, Messer HH. Hypochlorite injury to the lip following injection via a labial perforation. Case report. Aust Dent J. 1993;38:280-282. 36. Joffe E. Complication during root canal therapy following accidental extrusion of sodium hypochlorite through the apical foramen. Gen Dent. 1991;39:460-461. 37. Becking AG. Complications in the use of sodium hypochlorite during endodontic treatment. Report of three cases. Oral Surg Oral Med Oral Pathol. 1991;71:346348. 38. Neaverth EJ, Swindle R. A serious complication following the inadvertent injection of sodium hypochlorite outside the root canal system. Compend Cont Educ Dent. 1990;11:474-481. 39. Sabala CL, Powell SE. Sodium hypochlorite injection into periapical tissues. J Endod. 1989;15:490-492. 40. Grob R. [An incident with sodium hypochlorite—only my error?]. Schweiz Monatsschr Zahnmed. 1984;94:661-662. 41. Becker GL, Cohen S, Borer R. The sequelae of accidentally injecting sodium hypochlorite beyond the root apex. Report of a case. Oral Surg Oral Med Oral Pathol. 1974;38:633-638. 42. Kozol RD, Gillies C, Elgebaly SA. Effects of sodium hypochlorit e (Dakin’s solution) on cells of the wound module. Arch Surg. 1988;123:420-427. 43. Harrison JW. Irrigation of the root canal system. Dent Clin North Am. 1984;28:797-808. 44. Spangberg L. Instruments, materials, and devices. In: Cohen S, Burns RC, eds. Pathways of the Pulp. 9th ed. St Louis, Mo: Mosby; 1980:545-546. 45. Yesilsoy C, Whitaker E, Cleveland D, et al. Antimicrobial and toxic effects of established and potential root canal irrigants. J Endod. 1995;21:513-515. 46. Gomes BP, Ferraz CC, Vianna ME, et al. In vitro antimicrobial activity of several concentrations of sodium hypochlorite and chlorhexidine gluconate in the elimination of Enterococcus faecalis. Int Endod J. 2001;34:424-428. 47. Marais JT, Williams WP. Antimicrobial effectiveness of electro-chemically activated water as an endodontic irrigation solution. Int Endod J. 2001;34:237243.